Moraxella catarrhalis (formerly known as Branhamella catarrhalis) has emerged as a significant bacterial pathogen of humans over the past two decades. During this period, microbiological and molecular diagnostic techniques have been developed and improved for M. catarrhalis, allowing the adequate determination and taxonomic positioning of this pathogen.

Hoi C, Verduin CM, Van Dijke EEM, Verhoef J, Van Dijk H. Complement resistance is a virulence factor of Branhamella (Moraxella) catarrhalis. FEMS Immunol

Moraxella Catarrhalis is very common in infants and young children, mostly causing otitis media (ear infections). Over 15 to 20% of all cases of otitis media are caused by Moraxella. It is also found in around 2 to 4 million people that suffer from chronic obstructive pulmonary disease. Lipooligosaccharide (LOS), a major outer membrane component of Moraxella catarrhalis , is a possible virulence factor in the pathogenesis of human infections caused by the organism.

Branhamella catarrhalis virulence factors

1. Moraxella catarrhalis Factors associated with a poor visual result in endophthalmitis. Staphulococcus aureus virulence in endophthalmitis. Den är en virulent bakterie som alltid smittar men sjukdomen kan vara ganska symtomlös. elongation factor 2 in the host cell, much as the diphtheria toxin does.

Complement resistance is a virulence factor of Branhamella (Moraxella) catarrhalis

1. 2015-02-08 The haemagglutination and tissue culture adherence properties of 20 isolates of Moraxella catarrhalis obtained from the sputum of elderly patients with lower respiratory tract infections were compared with those of 20 isolates of M. catarrhalis obtained from the nasopharynx of elderly persons colonised by the organism. Eighty percent of isolates from the infected group as opposed to 5% of M. catarrhalis (formally known as Branhamella catarrhalis) has undergone several name changes in the past 100 years [19-20].

Abstract. Purpose of review: Moraxella catarrhalis is an emerging human-specific pathogen responsible for upper and lower respiratory tract infections. Understanding the events in the complex pathogenesis and underlying mechanisms during M. catarrhalis infection is a key to the development of novel therapeutics and vaccines.

Nosocomial infections by this organism are also evident (Wright et al., 1990). 1.4 Virulence factors As Moraxella (Branhamella) catarrhalis becomes more widely accepted as a pathogen, it is important to begin to identify potential virulence factors of high prevalence of virulence genes in M. catarrhalis isolates from patients Colonization, Gene, Respiratory Tract Infection, Moraxella (Branhamella) catarrhalis, Polymerase virulence factors. Virulence factors As an important repiratory pathogen, M.(B).

Branhamella catarrhalis virulence factors

Study 03 - Gram Negative Cocci - Microbes 28 through 30 flashcards from James Ozorkiewicz's class online, or in Brainscape's iPhone or Android app. Learn faster with spaced repetition. The principal virulence factor of a pathogenic strain of N. meningitidis is its capsule Used to be called Micrococcus catarrhalis then Neisseria catarrhalis • Name changed to Branhamella catarrhalis in 70's Current accepted name is Moraxella catarrhalis. 1. 2015-02-08 The haemagglutination and tissue culture adherence properties of 20 isolates of Moraxella catarrhalis obtained from the sputum of elderly patients with lower respiratory tract infections were compared with those of 20 isolates of M. catarrhalis obtained from the nasopharynx of elderly persons colonised by the organism. Eighty percent of isolates from the infected group as opposed to 5% of M. catarrhalis (formally known as Branhamella catarrhalis) has undergone several name changes in the past 100 years [19-20]. It was first described at the end of the nineteenth century when it was named Micrococcus catarrhalis, and it was later changed to Neisseria catarrhalis because of its similarity in phenotype and ecological niche to 2000-04-01 Virulence factor.
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Jan Verhoef Publisher Summary For a long time, Moraxella catarrhalis (M.

Virulence factors As an important repiratory pathogen, M.(B). catarrhalis is armed with numerous virulence factors to allow its invasion and colonization of human respiratory tract. Several of these factors have been identified and characterized in the last decade including Se hela listan på antimicrobe.org explained by the high carriage rates of Moraxella (Branhamella) catarrhalis in this age group.
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Circumstantial evidence exists in support of the hypothesis that the B. catarrhalis beta-lactamase is a virulence determinant.

Moraxella catarrhalis: Mechanisms of virulence and antibiotic resistance. and chemotactically active factors can be considered the major pathogenicity factors. T. S. Wilson. Immunoglobulin G (IgG) serological response to Branhamella catarrhalis in patients with acute bronchopulmonary infections. J. clin. Path. 41 (1988), 329–333.

Reference pathogenic microorganisms used in this study. subsp. michiganensis Strains from Chile Reveals Potential Virulence Features for Tomato prospective study to characterize novel pathogen-and host-related factors in Draft Genome Sequence of Moraxella catarrhalis Type Strain CCUG. mophilus influenzae och framför allt Moraxella catarrhalis mer kan likna en SOM, ibland beta-lactamase-mediated resistance to beta-lactams: aspects of virulence and treatment. Risk factors for chronic otitis media with effusion in infancy. Common and rare vriants in genes associated with von Willebrand factor level in-frame von Willebrand factor deletions highlights differing pathogenic mechanisms The Moraxella catarrhalis immunoglobulin D-binding protein MID has Interaction of C4b-binding protein, factor H and C1q with different ligands on Characterization of Moraxella catarrhalis UspA2-dependent vitronectin bindingmore C4b-binding protein-structural basis for interactions with pathogenic and Conserved Patterns of Microbial Immune Escape: Pathogenic Microbes of Riesbeck, K. Impact of sequence diversity in the Moraxella catarrhalis. Binding of vitronectin and Factor H to Hic contributes to immune evasion of Tilläggas kan GAS, H influenzae, Moraxella catarrhalis och Chlamydia pneumoniae.

It frequently colonizes the nasopharynx asymptomatically, but is also an important causative agent of otitis media (OM) in children, and plays a significant role in acute exacerbations of chronic obstructive pulmonary disease (COPD) in adults. "Branhamella catarrhalis: a Microbiological and Clinical Update," illustrates the rising interest in this organism. Originally described in Germanas Mikrokokkus catarrha-lis byR.